VCaP
1
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The VCaP cell line, derived from hormone-refractory prostate cancer tissue, displays significant expression of prostate-specific antigen (PSA), androgen receptor, cytokeratin-18, and prostatic acid phosphatase (PAP). Notably, it retains androgen sensitivity both in vitro and in vivo. Characterized by slow growth, VCaP cells require up to 48 hours to attach post-thaw and during subculturing. Typically taking a minimum of 2 weeks, they reach around 50% confluence, exhibiting a mix of adherent cells, floating clusters, and moderate to heavy debris. Initial attachment occurs in compact clusters and single cells, forming flattened epithelial-like islands upon proliferation.
Why choose VCaP from AcceGen?
The VCaP cell line from AcceGen is preferred due to its exceptional viability and quality, maintained in a sterile environment devoid of bacteria, fungi, and mycoplasma contamination. Furthermore, the cell line’s identity is ensured through the use of STR profiling, affirming its authenticity and consistency.
| Product Code | VCAP; Vcap; Vertebral Cancer of the Prostate |
| Species | Human |
| Cat.No | ABC-TC1272 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Prostate |
| Disease | Prostate Cancer |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Prostate Cancer Cell Lines |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
Saranyutanon, S., Deshmukh, S.K., Dasgupta, S., Pai, S., Singh, S. and Singh, A.P., 2020. Cellular and Molecular Progression of Prostate Cancer: Models for Basic and Preclinical Research. Cancers, 12(9), p.2651.
FOR RESEARCH USE ONLY
The VCaP cell line serves as a valuable cell-based model for human prostate cancer, enhancing the toolkit for studying the mechanisms driving prostate cancer progression and metastasis. Its application extends to investigating crucial factors like the human retrovirus XMRV (xenotropic murine leukemia virus-related virus) within prostate carcinoma. The cells are tumourigenic in SCID mice. With its expression of unaltered androgen receptor and ability to proliferate independently of androgens, the VCaP cell line is exceptionally suited for investigating the intricate dynamics of castration-resistant prostate cancer.
