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This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Species | Human |
Cat.No | ABC-KC2148 |
Product Category | Transfected Stable Cell Lines |
Size/Quantity | 100ug |
Shipping Info | Ice Pack |
Growth Conditions | 37 ℃, 5% CO2 |
Storage | Store TOP1MT KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles. |
Product Type | CRISPR Knockout Cell Lysate |
Host Cell | HEK293T |
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