TDG Knockout Cell Lysate
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The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008]
Species | Human |
Cat.No | ABC-KC2051 |
Product Category | Transfected Stable Cell Lines |
Size/Quantity | 100ug |
Shipping Info | Ice Pack |
Growth Conditions | 37 ℃, 5% CO2 |
Storage | Store TDG KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles. |
Product Type | CRISPR Knockout Cell Lysate |
Host Cell | HeLa |
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For research use only