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Tumor Cell Lines

TCMK-1

  • BSL

    1

  • 138
The cells ar5e SV40 transformed and are positive for SV40 T-antigen; About 2% of the cells are positive for SV40 viral antigen, but virus is not recoverable; Tested and found negative for ectromelia virus (mousepox)Tumorigenecity: noIsoenzyme: Histopathology: normalSubculture: Split ratio: Media change: Reverse transcritase: negativeProduction.
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The TCMK-1 cell line is a mouse renal tubular cell line originally derived from C3H mouse kidney tissue through SV-40 transformation. These cells exhibit a positive expression of SV40 T-antigen and possess a karyotype model number of 78, while ranging from 64 to 157, with most cells having 2-6 acrocentric chromosomes featuring secondary constrictions, along with 1-4 biarmed chromosomes per cell. Additionally, around 60% of the cells carry one or more minute chromosomes. It is recommended to subculture TCMK-1 cells at a ratio of 1:2 to 1:8 and renew the medium every 2 to 3 days to maintain their growth and viability.

 

Why choose TCMK-1 from AcceGen?

The TCMK-1 cells from AcceGen exhibit high viability and exceptional quality, ensuring reliable research outcomes. These cells are cryopreserved by experienced operators and undergo rigorous quality control measures. When incubated under optimal conditions, TCMK-1 cells provide a robust and dependable platform for various experimental applications.

Product Code

TCMK1; Transformed C3H Mouse Kidney-1

Species

Mouse-Weanling, Mus Musculus

Cat.No

ABC-TC1224

Product Category Tumor Cell Lines
Size/Quantity

1 vial

Cell Type

Epithelial

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Kidney

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Mouse Kidney Cell Lines

Citation

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Application

  • FOR RESEARCH USE ONLY

  • The TCMK-1 cell line serves as a valuable tool in various research applications related to renal injury, including investigations into mitochondrial injury, hypoxia/reoxygenation injury, and sepsis-induced acute kidney injury. Its utility extends to drug development endeavors aimed at preventing or ameliorating injury and inhibiting renal tubular cell apoptosis. TCMK-1 cells also play a crucial role in elucidating related regulation pathways, thereby supporting the development of alternative treatments for acute kidney injury, making them a pivotal resource in advancing our understanding and management of kidney-related pathologies.

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Tags

  • Epithelial (292)
  • Kidney (147)
  • Mouse (639)
  • Normal (1578)
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