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SLVL (VL51) cells, also known as VL51, are a B-cell line derived from a female patient with splenic lymphoma with circulating villous lymphocytes (SLVL). These cells exhibit monoclonality, indicating that they originate from a single cell with abnormal genotypes in the immunoglobulin heavy chain (IgH) gene and the T-cell receptor β (TCR β) gene. The VL51 cell line demonstrates a committed B-cell phenotype, as evidenced by the expression of CD10, CD19, CD20, and surface immunoglobulins. Additionally, VL51 cells are positive for Epstein-Barr virus nuclear antigen (EBNA). Morphologically, SLVL cells resemble lymphocytes and some of them attach to the surface of culture dishes, requiring pipetting during subculture.
Why choose SLVL from AcceGen?
The SLVL cell from AcceGen has various advantages for customers, such as high viability, standardized production, professional operation, and rigorous quality control measures. It was produced in a sterile environment, ensuring its integrity. Extensive testing confirms the absence of HIV-1, -2, HBV, HCV, bacteria, yeast, and mycoplasma. The cells exhibit high viability, enabling accurate physiological responses. Standardized production protocols ensure consistency, while professional operation and rigorous quality control measures uphold the product’s reliability. These features make the SLVL cell product safe, reliable, and suitable for a variety of research and experimental applications.
| Product Code | VL-51 |
| Species | Human |
| Cat.No | ABC-TC1054 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Lymphocyte-like |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Lymphoma Cell Lines |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
SLVL (VL51) cells have valuable applications in clarifying the leukemogenesis of SLVL and diagnosing B-cell disorders. They aid in understanding the underlying mechanisms of splenic lymphoma with circulating villous lymphocytes and identifying genetic and molecular abnormalities involved in its development. Additionally, the hematologic, immunophenotypic, and molecular characteristics of SLVL cells help diagnose and classify various B-cell disorders. By analyzing these cells, researchers gain insights into disease progression, potential therapeutic targets, and improved diagnostic approaches. Overall, SLVL cells enhance our understanding of SLVL leukemogenesis and contribute to the diagnosis of B-cell disorders.
