SLC2A4 Knockout Cell Lysate

This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an RI-regulated facilitative glucose transporter. In the absence of RI, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of RI stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with nonRI-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008]