For research use only
| Cat No. | ABC-TC1049 |
| Product Type | Human Nerve Tumors Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Bone Marrow |
| Product Code | SK N SH; SKN-SH; SK-NSH; SKNSH; NSH |
SK-N-SH is a human neuroblastoma cell line ideal for neuronal differentiation studies, dopamine metabolism, and cytotoxicity assays in neuro-oncology.
SK-N-SH is a human neuroblastoma cell line derived from a metastatic bone lesion of a 4-year-old female patient with pediatric neuroblastoma. These cells exhibit morphological heterogeneity, growing as both adherent epithelial-like cells and floating neuroblastic aggregates. Under specific conditions, SK-N-SH cells can differentiate into neuron- or glial-like phenotypes, making them a versatile in vitro model. They express neural markers including neurofilament proteins, synaptophysin, and neuron-specific enolase (NSE), consistent with their neural crest origin. Some subpopulations carry MYCN amplification, contributing to tumorigenic potential. SK-N-SH cells are widely used in studies of neuroblastoma pathophysiology, neuronal differentiation, and screening of chemotherapeutic and neurotoxic agents, making them a valuable tool in neuro-oncology and developmental neurobiology research.
| Product Code | SK N SH; SKN-SH; SK-NSH; SKNSH; NSH |
| Species | Human |
| Cat.No | ABC-TC1049 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Bone Marrow |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Nerve Tumors Cell Lines |
The SK-N-SH cell line is a widely used model in neuroscience research. It facilitates studies on neuronal differentiation, neurodevelopment, and signal transduction. Researchers use these cells to explore the mechanisms of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, and to evaluate neurotoxicity and neuroprotective agents. Their ability to differentiate into neuron-like cells also supports research into brain development and neurological drug discovery.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
