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Tumor Cell Lines

RIN-5F

  • BSL

    1

  • 127
Rat islet cell tumour. RIN-5F is a secondary clone of the rat islet tumour cell line RIN-m. Cloning was performed by limited dilution in RPMI 1640, 10%FBS and 20% conditioned medium. The conditioned medium contained somatotropic hormonees and prolactin being produced by rat pituitary tumour cells GH3.
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  • High Purity Levels
  • Precision and Reliability
  • Customization Options

RIN-5F is a derivative of the rat islet tumor cell line RIN-m, and it boasts distinctive features. These cells are renowned for their insulin secretion capacity and their high levels of the crucial APUD enzyme, L-dopa-decarboxylase. What sets them apart is their possession of membrane-bound secretory granules, facilitating insulin release, while interestingly, they do not produce somatostatin, unlike their parental line. During subculturing, these cells take approximately 3 days to attach fully, forming small clusters instead of a continuous monolayer. It is recommended to use a subcultivation ratio of 1:3 to 1:6, with medium renewal required every 3 to 4 days to sustain their growth.

 

Why choose RIN-5F from AcceGen?

RIN-5F cells from AcceGen exhibit exceptional features, boasting high viability and quality. These cells are meticulously incubated under optimal conditions and cryopreserved using advanced techniques, ensuring their robustness and longevity. They are delivered sterile and are rigorously quality-controlled, guaranteeing their reliability for a wide range of research applications.

Product Code

RIN m5F; Rin-M-5F; Rin-m-5F; RIN-m 5F; RINm-5F; RINm5F; RIN-m clone 5F; RIN Cl-5F; RIN-5F; Rin-5F; RIN 5F; RIN5F; m5F; 5F

Species

Rattus Norvegicus

Cat.No

ABC-TC0970

Product Category Tumor Cell Lines
Size/Quantity

1 vial

Cell Type

Epithelial

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Pancreas

Disease

Insulinoma

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Rat Pancreas Cancer Cell Lines

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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Application

  • FOR RESEARCH USE ONLY

  • RIN-5F cells serve as invaluable models for investigating the intricacies of pancreatic islet cell biology. They provide a unique platform for delving into the mechanisms that govern the synthesis, storage, and secretion of insulin and somatostatin, shedding light on crucial aspects of endocrine regulation. This cell line’s ability to mimic these processes makes it an essential tool for research aimed at unraveling the mysteries of pancreatic islet function and associated diseases like diabetes and neuroendocrine tumors.

Inquiring RIN-5F

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

  • Epithelial (292)
  • Pancreas (43)
  • Pancreas Cancer (28)
  • Rat (330)
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