Rat Schwann Cells
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Rat Schwann cells (RSC) are key glial cells in the peripheral nervous system, supporting neurons physically and chemically. They wrap around peripheral axons, forming myelin sheaths that insulate and enhance signal conduction. RSC are crucial for axon and neuron growth, survival, and morphology. Studies suggest they facilitate neuronal restoration and spinal cord regeneration. When an axon is damaged, surrounding Schwann cells aid in its clearance, creating a pathway for new axon growth. The population of Schwann cells is tightly regulated, and growth factors like PDGF, FGF, and neuregulin promote their proliferation.
Why choose Rat Schwann Cells from AcceGen?
The Rat Schwann cell product boasts several notable features. It is characterized by positive expression of S100 and GFAP, confirming of its identity. These Schwann cells demonstrate high viability (>90% at 24 hours post-plating), and they are both expandable and homogeneous. Furthermore, rigorous testing ensures that they are free from mycoplasma, bacteria, yeast, and fungi. Additionally, these Rat Schwann Cells are guaranteed to undergo at least five population doublings when subjected to the provided conditions by AcceGen.
| Species | Rat |
| Cat.No | ABC-TC4214 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | Schwann Cell |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Peripheral Nervous System |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Rat Primary Cells |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
Rat Schwann cells offer a valuable model for developmental studies and have clinical implications in neuropathies, nerve regeneration, and central nervous system (CNS) repair. Their biology is crucial to understand for potential therapeutic applications. Schwann cells or their precursors show promise in facilitating CNS repair through implants and bioengineered scaffolds. Due to their unique properties and interactions with neurons, they play a significant role in neurology, tissue engineering, and regenerative medicine. By exploring Schwann cell biology, we can advance our understanding and develop innovative approaches for addressing neurological disorders and promoting nerve regeneration.
