For research use only
| Cat No. | ABC-TC4214 |
| Product Type | Rat Primary Cells |
| Cell Type | Schwann Cell |
| Species | Rat |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Peripheral Nervous System |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Rat Schwann cells derived from peripheral nerves exhibit bipolar shape and form myelin. They are widely used in models of nerve injury and regeneration.
Rat Schwann Cells (RSCs) are glial cells derived from the peripheral nervous system (PNS) of Rattus norvegicus (rat) sciatic nerves. Morphologically, RSCs are usually bipolar or tripolar spindle-shaped in vitro culture, with slender cell bodies and obvious processes, and often grow in a monolayer adherent manner. The main functions of RSCs include forming myelin sheaths to wrap axons which promote efficient conduction of nerve signals, secreting neurotrophic factors (such as NGF and BDNF) to support neuronal survival and regeneration, and participating in the injury repair and microenvironment regulation of PNS. RSCs express key markers such as S100, P0, and myelin basic protein (MBP), indicative of their Schwann cell identity and function. They play a critical role in nerve regeneration and repair, and are widely used to study peripheral neuropathies, demyelinating diseases, and nerve injury mechanisms.
| Product Code | Rat Schwann Cells, Rat Schwann Cell Culture, Schwann Cells |
| Species | Rat |
| Cat.No | ABC-TC4214 |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | Schwann Cell |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Peripheral Nervous System |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Rat Primary Cells |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Rat Schwann Cells (RSCs) serve as a vital in vitro model for studying peripheral nerve development, regeneration, and disease. These glial cells enable research into myelination processes, axon-glia interactions, and the molecular mechanisms underlying neuropathies such as Charcot-Marie-Tooth disease and Guillain-Barré syndrome. RSCs are particularly valuable for nerve injury repair studies, including the testing of biomaterials for nerve conduits and the evaluation of neurotrophic factor therapies. Their applications extend to drug screening for demyelinating disorders and the development of cell-based therapies for peripheral nerve repair, making them indispensable for both basic neuroscience and translational medicine.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
