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Immortalized Cell Lines

Rat Cochlear Microglial Cell Line

  • BSL

    1

  • 131
Mocha cells are a rat cochlear microglial cell line. They were developed from an immunomagnetically enriched population of CD11b+ cells from P3 rat cochlea and Immortalised with the 12S E1A gene of adenovirus in a replication-incompetent retroviral vector.Microglia are a unique lineage of mononuclear phagocytic cells that play an essential role in development, immunological defense […]
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Species

Rat

Cat.No

ABI-TC039D

Product Category Immortalized Cell Lines
Size/Quantity

1 vial

Cell Type

Microglial

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Cochlea

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Immortalized Cell Line

Immortalization Method

immortalized with the 12S E1A gene of adenovirus in a replication-incompetent retroviral vector.

Description

Rat Cochlear Microglial Cell Line were developed from an immunomagnetically enriched population of CD11b+ cells from P3 rat cochlea and Immortalised with the 12S E1A gene of adenovirus in a replication-incompetent retroviral vector. Microglia are a unique lineage of mononuclear phagocytic cells that play an essential role in development, immunological defense and in- flammatory processes in the central nervous system. Microglia account for 10-15% of all cells found within the brain. As the resident macrophage cells, they act as the first and main form of active immune defence in the central nervous system (CNS).

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Citation

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Application

  • For research use only

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