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Primary Cells

Rat Cardiac Microvascular Endothelial Cells

  • BSL

    1

  • 90
Rat Cardiac Microvascular Endothelial Cells (RCMEC) are isolated from adult Sprague Dawley rat heart tissue. RCMEC are cryopreserved from passage one culture. RCMEC are guaranteed to further expand for 10 population doublings at the conditions recommended by AcceGen.
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Rat Cardiac Microvascular Endothelial Cells (RCMEC) are derived from rat heart tissue and play pivotal roles in myocardial function. These specialized cells are responsible for regulating vascular tone by releasing and breaking down endothelium-derived vasoactive factors, thus modulating the levels of vasoconstrictors and vasodilators through enzymatic processes. This intricate control extends to influencing myocardial contractile behavior. Beyond vascular function, RCMEC are integral in regulating leukocyte recruitment, inflammation, and angiogenesis within the microvasculature. Notably, they exhibit the ability to trans-differentiate into myofibroblasts, hinting at their involvement in matrix accumulation and fibrotic disorders. RCMEC express key markers such as vWF/Factor VIII and CD31 (PECAM).

 

Why choose Rat Cardiac Microvascular Endothelial Cells from AcceGen?

AcceGen’s Rat Cardiac Microvascular Endothelial Cells (RCMEC) are cryopreserved at passage one and shipped in a frozen state, ensuring their viability upon arrival. Each vial of RCMEC contains over 0.5×106 viable cells, and they are guaranteed to expand for up to 5 population doublings when following the provided technical sheet instructions, making them a reliable and versatile resource for research purposes.

Product Code

RCMEC

Species

Rat

Cat.No

ABC-TC4108

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial

Cell Type

Endothelial

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Heart

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Rat Primary Cells

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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Application

  • FOR RESEARCH USE ONLY

  • Rat Cardiac Microvascular Endothelial Cells (RCMEC) serve as a crucial asset for delving into the physiological and pathophysiological aspects of cardiac microvascular endothelium. These cells facilitate a deeper exploration of the intricacies of the cardiac microvasculature, offering insights into the pathophysiology of inflammatory cardiomyopathies and their implications. By studying RCMEC, researchers can unravel critical information concerning their role in cardiac function and disease, ultimately contributing to a better understanding of these complex cardiovascular conditions.

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