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QGP-1 | ||||
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| Product Name | QGP-1 | |||
| Price | Get Quote | |||
| Product Code | QGP 1; QGP1 | |||
| Cat.No | ABC-TC0918 | Species | Human | |
| Size/Quantity | 1 vial | Biosafety Level | 1 | |
| Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
| Description | QGP-1 is a neuroendocrine tumor cell line of pancreatic origin and can produce carcinoembryonic antigen (CEA). It originates from the neuroendocrine system in the pancreas, as confirmed by the expression of the neuronal marker, synaptophysin. The expression of transcription factors involving neuroendocrine cell differentiation in the pancreas was observed in QGP-1 cells.
Why choose QGP-1 from AcceGen? AcceGen provides TE671 with numerous beneficial characteristics. We maintain strict sterility standards, ensuring the absence of bacterial, fungal, and mycoplasma contamination. Our exceptional cryopreservation techniques guarantee high cell viability, resulting in reliable experimental outcomes. | |||
| Source Organ | Pancreas | |||
| Recommended Medium And Supplement | RPMI 1640 + 10% FBS | |||
| Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
| Application | FOR RESEARCH USE ONLY Panceras neuroendocrine tumors (panNET) are relatively rare pancreatic neoplasms, with an incidence of 0.43 per 100 000, and their clinical options are limited. However, the rates have increased rapidly in recent years, emphasizing the urgency to find novel therapies for panNET. QGP-1 can be useful as an in vitro model or in establishing a in vivo model for the drug development of neuroendocrine tumors (NET). QGP-1 is also a model of human enterochromaffin (EC) cells used to investigate the transient receptor potential ankyrin1 channel (TRPA1) due to a high expression of TRPA1 and EC cell marker genes. | |||
| Growth Conditions | 37 ℃, 5% CO2 | |||
| Cell Type | Epithelial-like | |||
| Product Type | Human Pancreas Cancer Cell Lines | |||
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Moreover, QGP-1 exhibited elevated gene expression levels related to immature or non-functional β/δ-cells genes, or pancreatic endocrine progenitors. QGP-1 is identified as G3 carcinomas by a Ki-67 (nuclear proliferation factor) labeling index of 82.6%±1.0%. When it was established in 1980, the doubling time of QGP-1 was about 84 hours (3.5 days), but this time was detected to be shorter, 38 hours, in 2018. With the use of these years, QGP-1 might become more malignant in culture. QGP-1 has the aberrant chromosome with a ploidy of 4.
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