PF-382
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PF-382 is a human T cell line derived from the pleural effusion of a young child diagnosed with T-acute lymphoblastic leukemia (T-ALL). These cells exhibit suppressive characteristics, both phenotypically and functionally. With a modal number of 46 chromosomes, PF-382 cells display a prevalent chromosomal abnormality involving a translocation between chromosome X and chromosome 15 (46X,Xq–,15p+). They demonstrate reactivity to OKT6, Leu-1, and Leu-9 monoclonal antibodies, which identify early T-lymphocytes, while expressing the more mature OKT8 antigen. Notably, these cells are unable to produce interleukin-2 and interferon spontaneously or in response to mitogen stimulation.
Why choose PF-382 from AcceGen?
Choosing PF-382 from AcceGen ensures high-quality and viable cells, as they are handled by professional operators in sterile conditions, incubated and cryopreserved under optimal settings, guaranteeing the best possible performance for research and experimental needs.
| Product Code | PF382 |
| Species | Human |
| Cat.No | ABC-TC481S |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Pleural Effusion |
| Storage | Liquid Nitrogen |
| Product Type | Human Leukemia Cell Lines |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
The unique property of PF-382 cells to secrete a soluble factor(s) with the capacity to influence the differentiation of the B-cell compartment makes them an important tool for studying the complex interplay between T-cell subsets and other hematopoietic cell lineages. This cell line holds significant potential as a valuable model system for investigating the mechanisms and interrelationships involved in the regulation of B-cell development and function, providing insights into the broader field of hematopoiesis.
