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NUDT5 Knockout Cell Lysate

  • BSL
  • 88
This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium […]
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Home | Transfected Stable Cell Lines | Knockout Cell Lysate | NUDT5 Knockout Cell Lysate
Species

Human
Cat.No

ABC-KC1343
Product Category Transfected Stable Cell Lines
Size/Quantity

100ug
Shipping Info

Ice Pack
Growth Conditions

37 ℃, 5% CO2
Storage

Store NUDT5 KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles.
Product Type

CRISPR Knockout Cell Lysate
Host Cell

HEK293T

Description

This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors. [provided by RefSeq, Aug 2013]

AcceGen Frozen Cells & Cell Lines 1 vial
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