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| Product Code | NEC-8 |
| Species | Human |
| Cat.No | ABL-TC0464 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Testis |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Germ Cell Cancer Cell Lines |
NEC8 is a human testicular embryonal carcinoma cell line derived from a surgical specimen. These cells exhibit a distinctive growth pattern, forming tightly packed, flat epithelial colonies with polygonal cells that gradually accumulate at the colony’s center. Under ultrastructure examination, NEC8 cells display prominent desmosomes and microvilli at the cell membrane. Notably, the cytoplasm of NEC8 cells is characterized by a high abundance of glycogen granules, leading to a strong PAS reaction. In vitro, NEC8 cells consist primarily of embryonal carcinoma cells with the potential for trophoblastic differentiation. When implanted in nude mice, NEC8 cells give rise to pure embryonal carcinoma tumors, showcasing their utility in research and modeling.
Why choose NEC8 from AcceGen?
NEC8 cells from AcceGen are characterized by their exceptional viability and quality, cultivated under optimal conditions, and cryopreserved by skilled technicians to ensure their stability and performance. These cells are delivered in a sterile condition and undergo thorough quality control measures to guarantee they are free from mycoplasma, bacterial, and fungal contamination, making them a reliable and trustworthy resource for various research applications.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
The NEC8 cell line plays a crucial role in cancer research, particularly in the study of testicular embryonal carcinomas. It serves as a valuable model for investigating the molecular mechanisms underlying the development and progression of these tumors. Additionally, NEC8 cells are instrumental in identifying factors responsible for chemotherapeutic resistance in testicular germ cell tumors, offering insights into potential strategies to overcome this resistance. Moreover, they are instrumental in clarifying novel immunotherapy targets, paving the way for the development of innovative approaches to combat these aggressive malignancies.
