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Tumor Cell Lines

NCI-H146

  • BSL
  • 66
Human Lung Carcinoma cell line. The NCI-H146 cell line was derived by A.F. Gazdar and associates in 1979 from the pleural fluid of a patient with small cell cancer of the lung. The bone marrow specimen was taken prior to therapy. The line expresses elevated levels of four biochemical markers (neuron specific enolase, brain isoenzyme […]
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Human Lung Carcinoma cell line. The NCI-H146 cell line was derived by A.F. Gazdar and associates in 1979 from the pleural fluid of a patient with small cell cancer of the lung. The bone marrow specimen was taken prior to therapy. The line expresses elevated levels of four biochemical markers (neuron specific enolase, brain isoenzyme of creatine kinase, L-DOPA decarboxylase and bombesin-like immunoreactivity. The cells stain positively for vimentin and keratin, but are negative for neurofilament triplet protein. The cells produce relatively high amounts of c-myc mRNA, but c-myc DNA sequences are not amplified. The cells do not express vasopressin, oxytocin or gastrin releasing peptide.

Product Code

H146; H-146; NCIH146

Species

Human

Cat.No

ABC-TC602S

Product Category Tumor Cell Lines
Size/Quantity

1 vial

Cell Type

Epithelial

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Lung

Disease

Cancer

Storage

Liquid Nitrogen

Product Type

Human Lung Cancer Cell Lines

Citation

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Application

  • For research use only

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Tags

  • Epithelial (292)
  • Human (1729)
  • Lung (169)
  • Lung Cancer (78)
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