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| Species | Human |
| Cat.No | ABC-TC0724 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Nerve Tumors Cell Lines |
NB-1 is a human neuroblastoma cell line capable of in vitro differentiation by cAMP. It is a continuous and functional cell line with hypodiploidy and two marker chromosomes specific to this line. Isolated from a metastatic neck lymph node, the cells exist in floating and/or attached forms and grow effectively in soft agar media. Floating cells are light-refractile, spherical, and cluster together, suggesting an undifferentiated blast type.
Attached cells form fine meshworks on glass surfaces, connected with slender processes, indicative of a differentiated and mature state. These cells synthesize DOPA and HVA in vitro, exhibit positive catecholamine fluorescence, and demonstrate monoamine oxidase activity.
Why choose NB-1 from AcceGen?
Choosing NB-1 from AcceGen ensures high viability and quality, as the cells are sterile, mycoplasma-free, and incubated under optimal conditions. Moreover, AcceGen employs advanced cryopreservation techniques and maintains rigorous quality control, guaranteeing reliable and consistent results for research and experimentation purposes.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
The NB-1 cell line offers valuable applications in various research areas. It is used to study the in vitro differentiation ability of neuroblastoma cells, investigating both morphological and functional changes during differentiation. Additionally, NB-1 cells are employed to explore the radiosensitivity of human neuroblastoma cells, helping to understand their response to radiation therapy. Furthermore, researchers utilize this cell line to investigate genetic abnormalities linked to the pathogenesis of neuroblastomas. Finally, NB-1 cells are instrumental in predictive modeling of anticancer drug sensitivity, aiding in the development of personalized treatment strategies for neuroblastoma patients.
