MT-2
1
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MT-2 is a T-cell line derived from normal human cord leukocytes of a male infant by co-cultivation with leukemic T-cells from a female patient with adult T-cell leukemia (ATL). These cells exhibit T-cell characteristics, expressing receptors for sheep erythrocytes and complement, reacting with anti-T-cell and anti-Ia sera, but testing negative for Fc receptors, surface immunoglobulin, and Epstein-Barr virus nuclear antigen. Chromosome analysis confirms their cord lymphocyte origin, revealing a predominantly male diploid karyotype. Furthermore, MT-2 cells are persistently infected with type C virus particles (ATLV) and display positivity for ATL-associated antigens (ATLA), specifically recognized by ATL patient sera.
Why choose MT-2 from AcceGen?
The MT-2 cell line exhibits high viability and quality, maintaining sterility with negative results for bacteria, fungi, and mycoplasma. Additionally, their positive HTLV-1 status is verified through PCR, and their identity is established via STR analysis.
| Product Code | MT2; MT-2J; MT-2Org |
| Species | Human |
| Cat.No | ABC-TC0707 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Lymphoblast |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Lymphocyte |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Leukemia Cell Lines |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
The MT-2 cell line, with its phenotypic and functional resemblance to human regulatory T cells (Tregs), serves as a valuable resource for investigating Treg biology. Notably, MT-2 cells harbor HTLV-1 and facilitate HIV growth, making them pivotal in elucidating viral interactions. This cell line is indispensable in advancing our understanding of MT-2 cell tropism, a critical factor in clinical trials and treatment selection for patients, particularly in the context of infectious diseases.
