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Mouse NK cells are present in various lymphoid and non-lymphoid tissues, including spleen, liver, lungs, blood, bone marrow, lymph nodes, and thymus. These mature NK cells exhibit surface markers like CD49b, CD122, CD161, NKG2D, NKp46, Ly49 receptors, CD11b, CD43, and newly identified CD27. They display versatile functionality, capable of lysing YAC-1 targets and producing cytokines (IFNγ and TNF) upon stimulation by IL-12, IL-18, or target cells. The splenic NK cell subset is involved in IFNγ secretion and natural cytotoxicity, hinting at a diverse functional composition within the mature NK-cell population in mice.
Why choose Mouse NK Cells from AcceGen?
Mouse NK cells from AcceGen is an excellent choice for exceptional quality and flexibility. These cells are sourced from various anticoagulant-treated peripheral blood or solid tissues, and can be tailored to custom formats and aliquot sizes. They are isolated using positive or negative immunomagnetic separation from mononuclear cells, with purity confirmed through flow cytometry and rigorous quality control, ensuring consistent and dependable cell lots for your research needs.
| Product Code | MNKCs |
| Species | Mouse |
| Cat.No | ABC-TC5527 |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | NK Cell |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Normal |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Primary Cells |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
Mouse NK cells are instrumental in unraveling the intricacies of NK cell biology and their pivotal role in the immune system. Their utility extends to a wide array of stimulation-dependent functional experiments, facilitating the assessment of cytokine production and cytotoxicity. These cells find extensive applications in drug discovery and development, assay validation, antibody-dependent cell-mediated cytotoxicity assays, and various other immunological studies. As a result, they not only enhance our comprehension of immune responses but also contribute significantly to research and clinical endeavors.
