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Mouse Hepatocytes | ||||
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Product Name | Mouse Hepatocytes | |||
Price | Get Quote | |||
Cat.No | ABC-TC3928 | Species | Mouse | |
Size/Quantity | 1 vial | Biosafety Level | 1 | |
Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
Description | Mouse hepatocytes, isolated from the mouse liver using a meticulous process involving anesthesia, vena cava cannulation, calcium chelation, and collagenase perfusion, represent a crucial component of liver research. These hepatocytes exhibit a distinctive polar morphology, with varying cell surface proteins across different 3D surfaces. To replicate this polar arrangement in vitro, researchers often overlay the hepatocyte monolayer with substances like collagen or basement membrane extracts. This meticulous isolation and cultivation of mouse hepatocytes provide valuable tools for studying liver function, metabolism, and drug testing, contributing to our understanding of hepatic biology and its applications in biomedical research.
Why choose Mouse Hepatocytes from AcceGen? Mouse Hepatocytes from AcceGen is preferred choice for research excellence. Our hepatocytes are freshly isolated upon demand, boasting exceptional viability and minimal batch-to-batch variation. We maintain stringent quality control, closely monitoring cell morphology, attachment efficiency, monolayer confluency, and long-term viability stability for cryopreserved hepatocytes, ensuring reliable and consistent results for your research needs. | |||
Disease | Normal | |||
Source Organ | Liver | |||
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. | |||
Recommended Medium And Supplement | ABM-TM3928 Mouse Hepatocytes Medium Kit | |||
Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). Dong, J., Adami, E., Chothani, S.P., Viswanathan, S., Ng, B., Lim, W.W., Singh, B.K., Zhou, J., Ko, N.S., Shekeran, S.G. and Tan, J., 2020. Autocrine IL11 cis-signaling in hepatocytes is an initiating nexus between lipotoxicity and non-alcoholic steatohepatitis. bioRxiv. | |||
Application | FOR RESEARCH USE ONLY Mouse hepatocytes play a pivotal role in several biomedical applications, primarily serving as a cost-effective alternative for studying liver-specific functions. Their utility extends to preclinical drug development and safety testing, offering insights into drug-induced liver toxicity. As primary hepatocytes, they provide an ex vivo model for understanding liver physiology, filling a crucial gap due to the limited availability and high cost of primary human hepatocytes. This versatile tool facilitates valuable research across various disciplines, making it indispensable for advancing our knowledge of liver biology and enhancing drug safety assessments. | |||
Growth Conditions | 37 ℃, 5% CO2 | |||
Cell Type | Hepatocyte | |||
Growth Mode | Adherent | |||
Product Type | Mouse Primary Cells | |||
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