+1 862-686-2696

  • Celebrate the holiday season with AcceGen’s highest discounts of the year. Merry Christmas and Happy New Year!

    Learn More
Featured Products
Primary Cells
Tumor Cell Lines
MicroRNA Agomir/Antagomir
Stem Cells
Immortalized Cell Lines
Transfected Stable Cell Lines
Nucleic Acid Kits
Explore Products
Cell
MicroRNA
Test and Analysis
Primary Cells

Mouse Hepatic Stellate Cells

  • BSL

    1

  • 94
Mouse Hepatic Stellate Cells (MHSteC) are isolated from Swiss mice. MHSteC are cryopreserved immediately after purification and delivered frozen (passage “0”). MHSteC is not recommend for expanding or long term cultures.
Request Your Custom Quote Today

Discover top-quality products tailored for scientific and medical research. Request a personalized quote today
to enhance your projects.

Get a Quote
  • High Purity Levels
  • Precision and Reliability
  • Customization Options
Home | Primary Cells | Animal Primary Cells | Mouse Primary cells | Mouse Hepatic Stellate Cells

Mouse Hepatic Stellate Cells (MHSC) are liver-specific mesenchymal cells derived from mouse liver, constituting 5-8% of total liver cells. Integral to liver homeostasis, maintenance, and regeneration, they excel at retinol metabolism. While quiescent in health, they harbor ample vitamin A lipid droplets, a major systemic reserve. However, in response to liver injury, MHSCs transition into an activated state marked by proliferation, contractility, and chemotaxis. This activation contributes to liver fibrosis, underpinning ailments like hepatitis B and C, fatty liver disease, and diabetes. Consequently, understanding MHSCs holds pivotal insights into treating chronic liver diseases and their associated complications, including cirrhosis.

 

Why choose Mouse Hepatic Stellate Cells from AcceGen?

Mouse Hepatic Stellate Cells from AcceGen are cryopreserved at passage one, ensuring cell viability upon delivery. They have been rigorously characterized through immunofluorescence targeting desmin and/or α-actin, ensuring their authenticity. Importantly, they have been screened and found negative for mycoplasma, bacteria, yeast, and fungi, ensuring their purity. AcceGen provides the assurance of successful culture continuation under the recommended conditions, making them a dependable choice for your research endeavors.

Product Code

MHSteC
Species

Mouse
Cat.No

ABC-TC3927
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Stellate Cell
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Liver
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Mouse Primary Cells

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

View More
AcceGen Frozen Cells & Cell Lines 1 vial
View Product Image

Application

  • FOR RESEARCH USE ONLY

  • Mouse Hepatic Stellate Cells offer a robust model system for delving into various facets of liver metabolism and pathophysiology. Their application spans diverse cell-based assays, including toxicity assessment, drug screening, and metabolic studies. They emerge as a crucial resource in the study of liver fibrosis, offering insights that could drive innovative therapeutic strategies for hepatic fibrosis treatment, ultimately aiming to enhance patient outcomes and mitigate the impact of chronic liver injury.

Frequently Asked Questions

  • What role do Mouse Hepatic Stellate Cells play in liver disease progression?

    These cells become activated during liver injury, contributing to fibrosis and scar tissue formation.

  • Can Mouse Hepatic Stellate Cells revert to a quiescent state after activation?

    In some cases, with appropriate signals, they can return to a less active, quiescent state, though this is limited.

  • How do Mouse Hepatic Stellate Cells interact with other liver cell types?

    They interact closely with hepatocytes and immune cells, influencing inflammation and tissue remodeling.

  • What signaling pathways are crucial for the activation of Mouse Hepatic Stellate Cells?

    Key pathways include TGF-β, PDGF, and Hedgehog signaling, which drive the activation and proliferation of these cells.

  • Online Inquiry
  • Product Reviews

Inquiring Mouse Hepatic Stellate Cells

We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time? Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

  • Liver (143)
  • Mouse (639)
  • Normal (1578)
  • Stellate (11)

Let's Advance Life Science Research Together

Contact Us
AcceGen Scroll Top Button