MOG-G-UVW
1
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MOG-G-UVW is a human brain astrocytoma cell line derived from an anaplastic astrocytoma of the normal adult brain. The cells exhibit glial and neoplastic characteristics, evidenced by the presence of dexamethasone-inducible glutamine synthetase, high-affinity uptake of y-aminobutyrate, aneuploidy, plasminogen activator activity, high saturation density, and angiogenic activity. These cells are telomerase-positive and lack alternative lengthening of telomeres (ALT). Notably, MOG-G-UVW expresses oxytocin receptors at both the mRNA and protein levels. Oxytocin treatment inhibits their cell proliferation, accompanied by an increase in intracellular cAMP levels. Furthermore, the cell line is TP53-wildtype and contains KATP channels.
Why choose MOG-G-UVW from AcceGen?
MOG-G-UVW cell line features high viability and quality, maintained by professional operators under strict sterility. Rigorous quality control ensures its authenticity and suitability for diverse research applications.
| Species | Human |
| Cat.No | ABC-TC0697 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Brain Cancer Cell Lines |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
The MOG-G-UVW cell line holds significant applications in various research areas. Firstly, it serves as a valuable model for tumorigenicity studies, particularly in the context of human anaplastic astrocytoma cells, enabling the investigation of the effects of growth factor receptor inhibitors alone or in combination with radiation. Secondly, it provides a platform to explore the biological impact of chemicals on cell proliferation in anaplastic astrocytomas. Additionally, MOG-G-UVW is utilized to elucidate the protective role of KATP channel openers. Moreover, the cell line has been instrumental in studying and determining the radiopharmaceutical applications of astatine-211, specifically by analyzing its reduction pattern. Lastly, MOG-G-UVW contributes significantly to virus studies, such as research related to HIV.
