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Tumor Cell Lines

MES-SA/Dx-5

  • BSL
  • 103
The multi drug-resistant cell line MES-SA/Dx5 was derived from the human uterine sarcoma cell line MES-SA which was originally obtained from a tumour from a 56-year-old Caucasian female at the time of hysterectomy. The Dx5 variant exhibits a 100-fold resistance to Adriamycin and has a reported doubling time of 30 hours. The two additional marker […]
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Product Code

MES-SA/Dx-5; MES-SA-Dx5; MES-SA Dx5; MESSA/Dx5; MESSA-DX5; MESSA Dx5; MESSADX5; Dx5

Species

Human

Cat.No

ABC-TC5562

Product Category Tumor Cell Lines
Size/Quantity

1 vial

Cell Type

Epithelial

Shipping Info

Dry ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Uterus

Disease

Uterus Sarcoma

Storage

Liquid Nitrogen

Product Type

Human Uterine Cancer Cell Lines

Description

The multi drug-resistant cell line MES-SA/Dx5 was derived from the human uterine sarcoma cell line MES-SA which was originally obtained from a tumour from a 56-year-old Caucasian female at the time of hysterectomy. The Dx5 variant exhibits a 100-fold resistance to Adriamycin and has a reported doubling time of 30 hours. The two additional marker chromosomes indicate clonal selection during drug selection. MES-SA/Dx-5 cells exhibit marked cross-resistance to a number of chemotherapeutic agents (including daunorubicin, dactinomycin, vincristine, taxol, colchicine) and moderate cross-resistance to MMC and melphalan.

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Citation

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Application

  • For research use only

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