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Species | Human |
Cat.No | ABC-KC1106 |
Product Category | Transfected Stable Cell Lines |
Size/Quantity | 100ug |
Shipping Info | Ice Pack |
Growth Conditions | 37 ℃, 5% CO2 |
Storage | Store MAP3K7 KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles. |
Product Type | CRISPR Knockout Cell Lysate |
Host Cell | HEK293T |
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
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For research use only