LN-319
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LN-319 cells are human brain epithelial cancer cells. LN-319 were derived from a left malignant glioma of a 69 year old Caucasian male with anaplastic astrocytoma grade III. LN-319 cells have a minimum of 40 population doubling levels when cultured using our protocol.
Why choose LN-319 from AcceGen?
Choose Accegen’s LN-319 cells for your research needs and benefit from a cell line that meets the highest standards of quality, purity, and performance.
Sterility Assurance: LN-319 cells undergo rigorous testing to guarantee sterility, providing confidence in your experiments. Our cells are thoroughly examined for contamination, including bacterial, fungal, Mycoplasma (PCR), and are verified negative for human pathogens.
Viability Excellence: Experience unparalleled post-thaw viability, with LN-319 cells consistently achieving over 95%. Our commitment to viability ensures the reliability and consistency you demand for your cell-based assays.
Identity Validation: We employ Short Tandem Repeat (STR) analysis, utilizing 16 probes (15 STR loci plus Amelogenin) to meticulously confirm the identity of LN-319 cells. This stringent process guarantees the authenticity of the cell line, providing you with accurate and reliable results.
Growth Validation: LN-319 cell growth is assessed based on morphological characteristics and immunocytochemistry of multiple undifferentiation markers. This thorough evaluation ensures that you receive cells with optimal growth patterns, essential for successful and reproducible experiments.
Product Code | LN 319; LN319 |
Species | Human |
Cat.No | ABC-TC499S |
Product Category | Tumor Cell Lines |
Size/Quantity | 1 vial |
Cell Type | Epithelial |
Shipping Info | Dry Ice |
Growth Conditions | 37 ℃, 5% CO2 |
Source Organ | Brain |
Storage | Liquid Nitrogen |
Product Type | Human Nerve Tumors Cell Lines |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
Here are some key applications of researching LN-319 in the scientific field.
Cancer Biology and Therapeutics: LN-319 cells serve as a valuable model for studying the underlying mechanisms of brain cancer development, progression, and response to therapeutic interventions. Researchers can explore novel targeted therapies, chemotherapy, and immunotherapies to improve treatment outcomes for patients with brain epithelial cancers.
Genomic and Proteomic Studies: Comprehensive genetic and proteomic analyses of LN-319 cells contribute to a deeper understanding of the molecular alterations associated with brain epithelial cancers. Identification of specific genetic markers and signaling pathways provides potential targets for diagnostic and therapeutic advancements.
Drug Screening and Development: LN-319 cells can be employed in drug screening assays to assess the efficacy and safety of potential anti-cancer compounds. The cell line serves as a valuable tool for the development of targeted therapies that aim to specifically inhibit cancer cell proliferation and survival.
Immunotherapy Research: Investigation of the interaction between LN-319 cells and the immune system facilitates the development of immunotherapeutic strategies for brain epithelial cancers. Understanding the immune landscape of these cancers can guide the development of immunomodulatory approaches for enhanced treatment outcomes.
Biomarker Discovery: LN-319 cells contribute to the discovery of biomarkers associated with brain epithelial cancers. Identification of reliable biomarkers aids in early detection, prognosis, and monitoring of treatment response.
Cell Biology and Signaling Pathways: LN-319 cells provide a platform to study the fundamental cellular and molecular processes underlying brain cancer. Investigations into cell cycle regulation, apoptosis, and signal transduction pathways deepen our knowledge of cancer biology.