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The KNS-60 cell line is a human glioma cell line commonly used in biomedical research, particularly in studies related to brain tumors and neuro-oncology. These cells were derived from a tumor in the brain of a 5-year-old girl with a diagnosis of glioblastoma multiforme. Glioblastoma multiforme is the most aggressive and malignant type of glioma, a type of brain tumor that originates from glial cells in the central nervous system.
Derived from this tumor specimen, the KNS-60 cell line serves as a crucial tool for investigating glioma biology, tumor heterogeneity, and treatment strategies. Notably, the recovery ratio of KNS-60 cells shows a statistically significant increase between the 3rd and 5th passages, enhancing their utility for experimental studies and drug screening in neuro-oncology research.
Why choose ABC-TC05333 KNS-60 from AcceGen?
High-Quality Assurance
KNS-60 cell line offered by AcceGen is meticulously quality-controlled to ensure the absence of HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi, guaranteeing the integrity and safety of your experiments.
Authentic Origin
AcceGen’s KNS-60 cell line is sourced from reputable suppliers and authenticated to ensure genetic stability and phenotypic consistency, providing researchers with confidence in their experimental outcomes.
Convenient Availability
The KNS-60 cell line is conveniently packaged and delivered frozen, allowing for easy storage and transportation, ensuring accessibility and convenience for researchers worldwide.
| Product Code | KNS 60; KNS60 |
| Species | Human |
| Cat.No | ABC-TC0533 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Brain |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Nerve Tumors Cell Lines |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
The KNS-60 cell line, has various applications in scientific research, particularly in the fields of cancer biology, neuro-oncology, and drug development. Here are some key applications of the KNS-60 cell line in science research:
Glioma Biology Studies
KNS-60 cells serve as a valuable model for studying the biology of gliomas, a type of brain tumor. Researchers can investigate the molecular and cellular mechanisms underlying glioma development, progression, and response to treatments.
Drug Screening and Development
The KNS-60 cell line is often used in drug screening assays to evaluate the efficacy of potential therapeutic agents against gliomas. Researchers can test a variety of compounds to identify potential candidates for further development as anti-glioma drugs.
Pharmacogenomics Research
Being cataloged in CellMinerCDB, the KNS-60 cell line is useful for pharmacogenomics research. Scientists can explore the correlation between gene expression profiles in KNS-60 cells and their responses to different drugs, contributing to personalized medicine approaches.
Radiation Sensitivity Studies
Researchers can use KNS-60 cells to study the sensitivity of gliomas to radiation therapy. This includes investigating the impact of radiation on cell viability, proliferation, and the molecular pathways involved in the response to radiation.
Tumor Microenvironment Studies
Researchers can use KNS-60 cells to investigate interactions between glioma cells and the tumor microenvironment. This includes studying how the surrounding tissue, immune cells, and extracellular matrix influence glioma behavior and response to therapies.
Developmental Biology and Stem Cell Research
Gliomas often contain a subpopulation of cancer stem cells. KNS-60 cells can be utilized to study these stem cell-like properties, contributing to our understanding of the cellular heterogeneity within gliomas.
In Vivo Tumor Xenografts
KNS-60 cells can be used to establish in vivo tumor xenograft models in mice. These models enable researchers to study the behavior of gliomas in a more complex and physiologically relevant environment.
