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The KNS-42 cell line is a human glioma cell line derived from a malignant glioma in 1972. It exhibits tumor angiogenesis factor in vitro and forms tumors when transplanted into mice with hereditary immunodeficiency. In sparse culture, the cells appear as polygonal and flat clusters, 
while dense culture shows predominantly polygonal cells with some small cells. The population doubling time ranges from 40 to 48 hours, influenced by factors like supplemented FBS quality, medium replacement intervals, and initial plating density. Hypertriploid chromosomes with an average count of 75 are observed, and the cells express GFAP, NSE, vimentin, and fibronectin, along with producing growth factors.
Why choose KNS-42 from AcceGen?
KNS-42 from AcceGen is a preferred choice due to its high viability and quality. The cells are guaranteed to free from mycoplasma, bacteria, fungi, and human pathogens. They are prepared by skilled operators using an optimal culture system and advanced cryopreservation techniques. AcceGen ensures rigorous quality control measures to maintain the integrity and reliability of the cell line.
| Product Code | KNS42 |
| Species | Human |
| Cat.No | ABC-TC0532 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Nerve Tumors Cell Lines |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
The KNS-42 cell line has various applications in glioma research. It serves as a valuable tool to evaluate the effectiveness of potential therapies, including radiation, for human glioma treatment. Additionally, KNS-42 cells are utilized to study the migratory characteristics of adult glioma cells and assess the treatment effects of small molecule inhibitors that aim to inhibit cell migration. Furthermore, this cell line is employed in investigating key oncogenes involved in glioblastoma, specifically their role in promoting the induction of epithelial-mesenchymal transition, a critical process in tumor progression.
