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Tumor Cell Lines

KMM-1

  • BSL

    1

  • 127
Small round-cell morphology, part is multinucleate cell.
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The KMM-1 cell line is a lymphocyte-like human multiple myeloma cell line that exhibits plasma cell characteristics. It displays a small round-cell morphology with some multinucleate cells, growing in suspension with noticeable nucleoli and rough endoplasmic reticulum. The cells possess an abnormal karyotype characterized by 47, X, -Y, Iq+, -2, +t(1:2) (cen:cen), +7, 12q+, 14q+, +mar, and lack Epstein-Barr virus-determined nuclear antigen. Surface markers include E rosette (-), IgG Fc receptor (-), C3 receptor (-), S-Ig (+), TdT (-), and asialo-GM1 (-). Notably, KMM-1 cells are shown to secrete immunoglobulins into the culture medium.

 

Why choose KMM-1 from AcceGen?

The KMM-1 cell line from AcceGen is characterized by its high viability and quality, maintained under optimal culture conditions. It is sterile and rigorously tested negative for mycoplasma, bacteria, fungi, and human pathogens. The cell line is efficiently preserved using advanced cryopreservation techniques.

Product Code

KMM1

Species

Human

Cat.No

ABC-TC0517

Product Category Tumor Cell Lines
Size/Quantity

1 vial

Cell Type

Lymphocyte-like

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Disease

Multiple Myeloma

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Human Myeloma Cell Lines

Citation

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Application

  • FOR RESEARCH USE ONLY

  • KMM-1 cells find diverse applications in research, notably in investigating antioxidant, antiproliferative, and immunostimulatory effects. They serve as a valuable model to study cancer cell apoptosis induction by potential inhibitors. Additionally, they are integral in preclinical trials involving immunophenotypic and immunotypic evaluations. Furthermore, KMM-1 cells hold promise in evaluating potential therapeutic agents, including therapeutic small guide RNAs, against multiple myeloma, contributing significantly to advancing therapeutic strategies in this context.

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High Viability
To succeed in cell culture
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To support a consistent result
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Tags

  • Human (1729)
  • Lymphocyte-like (30)
  • Myeloma (35)
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