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The KM-H2 cell line, established from the pleural effusion of a patient with Hodgkin’s disease of mixed cellular type in 1974, represents a vital model for studying human Hodgkin lymphoma. These cells, when cultured, exhibit a predominantly single, spherical morphology in suspension, characterized by a degree of heterogeneity in cell size, including bi- and polynucleated cells. Notably, KM-H2 cells display discernible acid phosphatase and nonspecific esterase activities. They are known for their propensity to form rosettes with T lymphocytes and exhibit positive receptor expression for C3b and the Fc portion of IgG. Furthermore, KM-H2 cells consistently express specific antigens, including Ki-1, Leu-M1, MCS1, HLA-DR, and OKT9. The standard subculturing protocol for KM-H2 cells involves a 1:2 to 1:4 split ratio every second day.
Why choose KM-H2 from AcceGen?
The KM-H2 cell line from AcceGen exhibits exceptional features, including high viability and quality, owing to its incubation under optimal conditions. Furthermore, it has been rigorously screened and found to be negative for mycoplasma and a range of other pathogens, such as EBV, HBV, HCV, HHV-8, HIV-1, HIV-2, HTLV-1/2, MLV, and SMRV, ensuring the integrity and reliability of this cell line for various research applications.
| Product Code | KM H-2; KMH2 |
| Species | Human |
| Cat.No | ABC-TC0514 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Lymphoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Lymphoma Cell Lines |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
The KM-H2 cell line plays a pivotal role in advancing our understanding of human Hodgkin’s lymphoma. It serves as a valuable tool for researchers to elucidate the factors and mechanisms supporting the growth and survival of Hodgkin lymphoma cells. Furthermore, KM-H2 cells are instrumental in the study of radioresistance within this context, aiding in the development of innovative therapeutic strategies to enhance treatment efficacy and patient outcomes in the battle against this challenging disease.
