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Transfected Stable Cell Lines

KIF5B-RET(G810S) BaF3 Cell Line

  • BSL

    1

  • 5
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The CCDC6-RET kinase protein is a fusion protein comprised of the CCDC6 (Coiled-Coil Domain-Containing Protein 6) and RET (Rearranged during Transfection) kinase proteins. This protein undergoes mutations in certain tumor cells, leading to its activation and promoting tumor growth and metastasis. The CCDC6-RET kinase protein is commonly seen in tumors like lung cancer and thyroid cancer, making it a potential therapeutic target. Research indicates that inhibiting the activity of the CCDC6-RET kinase protein can effectively suppress tumor growth and spread, providing new avenues for cancer treatment. Several tyrosine kinase inhibitors (TKIs) targeting the CCDC6-RET fusion gene are available, such as Cabozantinib, Selpercatinib, and Pralsetinib.BA/F3 cells are a type of IL-3-dependent precursor B cell, where certain protein kinases can substitute for IL-3 to promote the growth of Ba/F3 cells. By using inhibitors to counteract this effect, this can be utilized for research on kinase inhibitors.

Species

Mouse

Cat.No

ABC-X0357F

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial

Cell Type

Lymphocytes

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Lymphatic

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

BaF3

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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Application

  • For research use only

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