Ishikawa
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Ishikawa cells are a human endometrial adenocarcinoma cell line derived from a 39-year-old woman with endometrial adenocarcinoma. These cells exhibit a mosaic-like monolayer growth pattern and tend to form piles. Chromosomal analysis revealed a diploid range of modal chromosomal numbers.
When transplanted into athymic nude mice, the induced tumor exhibited well-differentiated adenocarcinoma characteristics similar to the original human tumor. The presence of estrogen receptor and progesterone receptor was observed both in the in vitro cultured cells and the induced tumor. Following exposure to chemicals with diverse estrogenic activity, Ishikawa cells can demonstrate a biologically significant estrogenic response.
Why choose Ishikawa from AcceGen?
Ishikawa cells from AcceGen are the preferred choice due to their high viability and quality. These cells are guaranteed to be sterile and have undergone incubation and cryopreservation processes carried out by professional operators under optimal standards. AcceGen ensures rigorous quality control measures, making their Ishikawa cells a reliable option for various research applications.
| Product Code | ISHIKAWA; ISHI |
| Species | Human |
| Cat.No | ABC-TC1320 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial-like |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Uterus |
| Storage | Liquid Nitrogen |
| Product Type | Human Uterine Cancer Cell Lines |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
Ishikawa cells find valuable applications in various fundamental research domains, including reproductive biology and molecular science. They serve as a reliable in vitro model for evaluating the potential estrogenic activity of chemicals. These cells are employed to assess the impact of estrogen agonists/antagonists on cell proliferation, as well as gene and protein expression. Moreover, Ishikawa cells are utilized as a testing material to evaluate the anticancer properties of drugs by monitoring alterations in morphology and biophysical properties.
