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INS Knockout Cell Lysate

  • BSL
  • 45
After removal of the precursor signal peptide, proRI is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form RI, and C-peptide. Binding of RI to the RI receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been […]
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Home | Transfected Stable Cell Lines | Knockout Cell Lysate | INS Knockout Cell Lysate
Species

Human
Cat.No

ABC-KC0927
Product Category Transfected Stable Cell Lines
Size/Quantity

100ug
Shipping Info

Ice Pack
Growth Conditions

37 ℃, 5% CO2
Storage

Store INS KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles.
Product Type

CRISPR Knockout Cell Lysate
Host Cell

HeLa

Description

After removal of the precursor signal peptide, proRI is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form RI, and C-peptide. Binding of RI to the RI receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5′ region and with the IGF2 gene at the 3′ region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

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