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Immortalized Human Fibroblast-Like Synoviocyte | ||||
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Product Name | Immortalized Human Fibroblast-Like Synoviocyte | |||
Price | Get Quote | |||
Cat.No | ABI-H0003X | Species | Human | |
Size/Quantity | 1 vial | Biosafety Level | 1 | |
Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
Description | Immortalized Human Fibroblast-Like Synoviocytes are derived by immortalizing primary human synoviocytes obtained from healthy synovial tissue through the introduction of SV40 Large T antigen. As the predominant cell type in normal synovial tissue, Human Fibroblast-Like Synoviocytes constitute the synovial lining layer, playing a crucial role in joint health. Responsible for synthesizing synovial fluid, these synoviocytes facilitate absorption in the joint cavity and regulate blood/synovial fluid exchanges. Notably, they exhibit characteristics such as anchorage-independent growth and the secretion of various effector molecules, contributing to inflammation and joint destruction.
Why choose Immortalized Human Fibroblast-Like Synoviocyte from AcceGen? AcceGen’s Immortalized Human Fibroblast-Like Synoviocytes (IM-HS) exhibit exceptional features, boasting high viability and quality. Each vial contains over 1 million viable cells, ensuring robust and reliable experimental outcomes. AcceGen further enhances the user experience by providing optimized medium and reagents, rigorously quality tested as a global solution to maximize the performance of in vitro IM-HS culture. | |||
Disease | Normal | |||
Source Organ | Synovium | |||
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. | |||
Recommended Medium And Supplement | ABI-M0003X Human Fibroblast-Like Synoviocyte Medium Kit | |||
Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
Application | FOR RESEARCH USE ONLY Immortalized Human Fibroblast-Like Synoviocytes offer a valuable cellular model for investigating synoviocyte physiology and the pathogenesis of joint diseases. Serving as a platform to explore synovial tissue organization and morphogenesis, these cells provide crucial insights and represent a potential therapeutic target. Moreover, their utility extends to the establishment of in vitro disease models for high throughput and high content screening, enhancing the efficiency of research focused on understanding and treating various conditions affecting the joints. | |||
Growth Conditions | 37 ℃, 5% CO2 | |||
Cell Type | Fibroblast-Like | |||
Growth Mode | Adherent | |||
Product Type | Immortalized Cell Line | |||
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