Home > Products > Primary Cells > Human Primary Cells > Blood System Primary Cells >
Human Valvular Interstitial Cells | ||||
|---|---|---|---|---|
| Product Name | Human Valvular Interstitial Cells | |||
| Price | Get Quote | |||
| Cat.No | ABC-TC3866 | Species | Human | |
| Size/Quantity | 1 vial | Biosafety Level | 1 | |
| Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
| Description |
Why choose Human Valvular Interstitial Cells from AcceGen? AcceGen’s Human Valvular Interstitial Cells (VICs) are derived from healthy human valves, cryopreserved at passage one, and delivered in a frozen state, with each vial containing over 0.5×106 viable cells. These cells are guaranteed to expand for 10 population doublings when following AcceGen’s instructions and have been rigorously tested for mycoplasma, bacteria, yeast, and fungi, ensuring their quality and reliability for research purposes. | |||
| Disease | Normal | |||
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. | |||
| Recommended Medium And Supplement | ABM-TM3866 Human Valvular Interstitial Cells Medium Kit | |||
| Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
| Application | FOR RESEARCH USE ONLY Human Valvular Interstitial Cells (VICs) serve as invaluable in vitro experimental systems, offering a platform for modeling various aspects of valve biology and pathobiology. Their application aids in shedding light on the intricate facets of VIC pathobiology, enhancing our comprehension of cellular heterogeneity regulation concerning valve structure and function in both healthy and diseased states. VICs thus stand as essential tools for advancing our knowledge of heart valve dynamics and disease mechanisms. | |||
| Growth Conditions | 37 ℃, 5% CO2 | |||
| Cell Type | Interstitial Cell | |||
| Product Type | Cardiac Cells | |||
| Product Image |  | |||
Human Valvular Interstitial Cells (VICs), the predominant cellular constituents within the heart valve, are ubiquitously distributed across its three distinct layers: the fibrosa, spongiosa, and ventricularis. These cells fulfill a pivotal role in the maintenance of valvular structural integrity. In response to pathological stimuli, valve tissue exhibits a pronounced accumulation of VICs, often concomitant with the infiltration of inflammatory cells, neovascularization, heightened extracellular matrix deposition, and subsequent fibrosis and calcification. Morphologically, VICs exhibit a hybrid phenotype, displaying characteristics reminiscent of both fibroblasts and smooth muscle cells, reflecting their multifaceted functional roles within the heart valve.Frequently Asked Questions
What is the source of Human Valvular Interstitial Cells?
These cells are derived from the heart valve tissue of healthy human donors or patients undergoing surgery.
Are Human Valvular Interstitial Cells suitable for valve disease modeling and research?
Yes, these cells are commonly used for studying valve-related diseases, fibrosis, and calcification.
What culture conditions are recommended for Human Valvular Interstitial Cells?
These cells should be cultured in a fibroblast-specific medium with growth supplements to maintain viability.
Can Human Valvular Interstitial Cells be used for drug testing related to heart valve therapies?
Yes, they are suitable for preclinical drug testing aimed at treating or preventing valvular diseases.
- ONLINE INQUIRY
- PRODUCT REVIEWS
Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
