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Transfected Stable Cell Lines

Human TIGIT (Luc) Jurkat Reporter Cell

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  • High Purity Levels
  • Precision and Reliability
  • Customization Options
Species

Human

Cat.No

ABC-RC181F

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial

Cell Type

T Lymphoblast

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Blood

Disease

Acute T Cell Leukemia

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Reporter Stable Cell Lines

Host Cell

Jurkat

Description

The Human TIGIT (Luc) Jurkat Reporter Cell was engineered to not only express the NFAT response element driving luciferase expressing systems, but also express the receptor full length human TIGIT (Gene ID: 201633), which can use to evaluate the potency of TIGIT blockade. When co-cultured with target cells expressing human CD155, the TIGIT/CD155 interaction inhibits TCR signaling and NFAT-mediated luminescence. Blocking the TIGIT/CD155 interaction by either anti-TIGIT or anti-CD155 antibodies releases the inhibitory signal and results in TCR activation and NFAT-mediated luminescence.

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Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

  • For research use only

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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