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Human Gastric Epithelial Cells

Product Name

Human Gastric Epithelial Cells

Price Get Quote
Cat.No

ABC-HP021X

Species

Human

Size/Quantity

1 vial

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

The inner layer of stomach is the gastric mucosa covered by mucous, which is secreted by a layer of simple columnar epithelial cells lining the lumen of stomach. The gastric epithelium invaginate to form gastric pits that connect to various glands that synthesis and secrete stomach juice.

Types of epithelial cells in stomach
Stomach epithelial cells consists of mucous cells, stomach epithelium chief cells, parietal cells and gastrin cells (G cells) that extends from stomach surface into gastric pits and glands. Injury, inflammation, or bacterial infection, especially Helicobacter pylori infection, on stomach can stimulate stomach epithelial cells proliferation and renewal.

Why choose Human Gastric Epithelial cells from AcceGen?
AcceGen Human gastric epithelial cells are isolated from normal human stomach tissue under authorization. Shortly after isolation, cells are cryopreserved at passage 3 in AcceGen cell culture media to ensure best quality. Each vial contains >5×10^5 cells in 1 ml volume. Our gastric epithelial cells culture can further expand for 2-4 passages at a split ration of 1:2 or 1:3 following AcceGen recommended protocol and culture conditions. Cells can form coherent monolayer and develop tight junction in AcceGen cell culture media with expression of epithelial marker cytokeratin and junction-associated marker E-cadherin or ZO-1.

Immortalized Human Gastric Epithelial Cells (hTert) are also available in AcceGen.

Disease

Normal

Source Organ

Gastric

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement

ABM-HP021X Human Gastric Epithelial Cells Medium Kit

Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

For research use only
AcceGen human gastric epithelial cells provide an excellent model for study gastrointestinal epithelial function and pathophysiology in vitro. The gastric epithelial cells can be used to study pathogenesis of H. pylori, screen effective antiulcer drugs, measure permeability and study gastric related digestive functions.

Key Features

-Backed by AcceGen advanced technology
-Cryopreserved for highest viability and plating efficiency
-Quality-tested for accurate results

Growth Conditions

37 ℃, 5% CO2

Cell Type

Epithelial

Growth Mode

Adherent

Product Type

Gastric Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial

Frequently Asked Questions

  • What are Human Gastric Epithelial Cells?

    Human Gastric Epithelial Cells are cells that line the surface of the stomach. They play a crucial role in secreting gastric acid, enzymes, and mucus, as well as forming a protective barrier against the harsh acidic environment of the stomach.

  • What functions do Human Gastric Epithelial Cells perform in the stomach?

    Human Gastric Epithelial Cells are responsible for secreting hydrochloric acid and digestive enzymes, producing mucus to protect the stomach lining from acid and mechanical damage, and absorbing some nutrients. They also contribute to the stomach’s barrier function, preventing pathogens from entering the body.

  • What are Human Gastric Epithelial Cells used for in research?

    Human Gastric Epithelial Cells are used in research to study gastric diseases such as gastric ulcers, gastritis, and gastric cancer. They are also utilized to investigate the effects of various drugs on the stomach lining, understand Helicobacter pylori infection mechanisms, and develop treatments for gastric disorders.

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