Human Skeletal Muscle Myoblasts

Human Skeletal Muscle Myoblasts are isolated from human muscle of normal donor. They play a crucial role in the regeneration of skeletal muscle. These cells undergo multiplication and subsequently fuse to form multinucleated myotubes, which ultimately mature into myofibers. This intricate developmental process takes place during muscle embryogenesis, postnatal muscle recovery following injury, or in conditions like Duchenne muscular dystrophy. While the fusion of myoblasts is a distinctive feature of skeletal muscle, those that do not contribute to muscle fibers take on the role of satellite cells. Remarkably, these myoblasts display heightened expression of FGF receptors and IGF during differentiation, and they exhibit responsiveness to physiological ligands including TGF-β1 and Myostatin. This underscores their paramount importance in the field of muscle biology.

Why choose Human Skeletal Muscle Myoblasts from AcceGen?

Human Skeletal Muscle Myoblasts from AcceGen is selected for reliable skeletal muscle research. These myoblasts, cryopreserved at passage one, offer convenient access with at least 5×10⁵ cells per vial. They assure differentiation of more than 50% within 48 hours, exhibit over 70% viability, and are extensively tested for contaminants, including mycoplasma, bacteria, fungi, and viruses like hepatitis B, hepatitis C, and HIV-1.