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Human Skeletal Muscle Myoblasts

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Product Name

Human Skeletal Muscle Myoblasts

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Product Code

HSkMM

Cat.No

ABC-TC3802

Species

Human

Size/Quantity

1 vial

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Human Skeletal Muscle Myoblasts are isolated from human muscle of normal donor. They play a crucial role in the regeneration of skeletal muscle. These cells undergo multiplication and subsequently fuse to form multinucleated myotubes, which ultimately mature into myofibers. This intricate developmental process takes place during muscle embryogenesis, postnatal muscle recovery following injury, or in conditions like Duchenne muscular dystrophy. Human Skeletal Muscle MyoblastsWhile the fusion of myoblasts is a distinctive feature of skeletal muscle, those that do not contribute to muscle fibers take on the role of satellite cells. Remarkably, these myoblasts display heightened expression of FGF receptors and IGF during differentiation, and they exhibit responsiveness to physiological ligands including TGF-β1 and Myostatin. This underscores their paramount importance in the field of muscle biology.

 

Why choose Human Skeletal Muscle Myoblasts from AcceGen?

Human Skeletal Muscle Myoblasts from AcceGen is selected for reliable skeletal muscle research. These myoblasts, cryopreserved at passage one, offer convenient access with at least 5×105 cells per vial. They assure differentiation of more than 50% within 48 hours, exhibit over 70% viability, and are extensively tested for contaminants, including mycoplasma, bacteria, fungi, and viruses like hepatitis B, hepatitis C, and HIV-1.

Disease

Normal

Source Organ

Muscle

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

Human Skeletal Muscle Myoblasts serve as a versatile toolset with broad applications. These cells provide an accessible and economical platform to investigate muscle atrophy, impaired glucose uptake, cellular development, and differentiation, insulin metabolism, and tissue repair. Additionally, they enable the creation of in vitro disease models for High Throughput and High Content Screening, enhancing drug development. Their utility extends to myotube development, co-culturing with other cell types, and promoting research in various aspects of muscle biology.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Myoblast

Growth Mode

Adherent

Product Type

Skeletal Muscle Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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