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Human Skeletal Muscle Microvascular Endothelial Cells

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Human Primary Skeletal Muscle Microvascular Endothelial Cells are isolated from human skeletal muscle tissue. Human Primary Skeletal Muscle Microvascular Endothelial Cells from Cell Biologics display typical cobblestone with large dark nuclei appearance under light microscopy. Cells are tested for expression of endothelial cell marker using antibody CD31.
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Home | Primary Cells | Human Primary Cells | Motion System Primary Cells | Human Skeletal Muscle Microvascular Endothelial Cells

Human skeletal muscle microvascular endothelial cells line the inner surface of microvascular capillaries within skeletal muscles. These cells serve as a critical barrier between circulating metabolites and tissues, playing a pivotal role in the regulation of nutrient exchange and immune cell migration. Muscle microvascular endothelial cells are characterized by their ability to uptake acetylated low-density lipoprotein (ac-LDL) and adenosine within the microvasculature, as well as their capacity to produce nitric oxide (NO).

Why choose Human Skeletal Muscle Microvascular Endothelial Cells from AcceGen?

Human skeletal muscle microvascular endothelial cells are isolated from human skeletal muscle tissue using AcceGen’s advanced techniques. Cells are cryopreserved to ensure the best viability. Each vial contains more than 5×10^5 cells in 1ml volume. Human skeletal muscle microvascular endothelial cells are quality tested with a cobblestone morphology and the expression of VE-cadherin and CD31/PECAM-1 by immunofluorescence.

Species

Human
Cat.No

ABC-H0025Y
Quality Control

All cell lots test negative for HIV-1, HBV, HCV, mycoplasma, yeast, fungi, and other pathogens.
Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Endothelial
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Skeletal Muscle
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Skeletal Muscle Cells

Citation

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AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • Human primary skeletal muscle microvascular endothelial cells provide an ideal model for in vitro study of the biology and biochemistry of endothelial cells. They have been used in a wide range of research applications, including endothelial dysfunction, skeletal muscle regeneration, and interaction with other skeletal muscle cells such as satellite cells.

Frequently Asked Questions

  • What are Human Skeletal Muscle Microvascular Endothelial Cells (HSkMECs)?

    Human Skeletal Muscle Microvascular Endothelial Cells (HSkMECs) are specialized cells derived from the microvasculature of human skeletal muscle tissue. They are pivotal in studying vascular functions and pathologies within skeletal muscle.

  • What are the key characteristics of HSkMECs？

    HSkMECs exhibit properties such as the expression of endothelial markers (e.g., CD31, VE-cadherin), the ability to form capillary-like structures in vitro, and responsiveness to angiogenic factors.

  • What are the primary research applications of HSkMECs?

    HSkMECs are used in studies focusing on muscle regeneration, angiogenesis, diabetes-related vascular complications, and muscle perfusion. They are used in research to provide insight into the microvascular functions and pathologies associated with skeletal muscle. Researchers use HSkMECs to investigate the mechanisms by which high glucose levels and insulin resistance affect microvascular endothelial function, offering a model to study the vascular complications often seen in diabetic patients.

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Tags

  • Endothelial (424)
  • Human (1729)
  • Normal (1578)
  • Skeletal Muscle (22)

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