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Human Retinal Pericyte Cells

Product Name

Human Retinal Pericyte Cells

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Cat.No

ABC-TC3790

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Human Retinal Pericyte Cells were initiated by centrifugal elutriation following dispersal of normal retinal tissue with collagenase and dispase.
These cells were originated using Complete Serum-Free Medium Kit With AcceSup™, are available at <12 Cumulative Population Doublings (CPD) in vitro [Passage 3] and were cryopreserved in aliquots of ~1.5×10^6 cells. This vial will initiate a Passage 4 cell culture in a 75cm2 flask.

Disease

Normal

Source Organ

Retina

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement

ABM-TM3790 Human Retinal Pericyte Cells Medium Kit

Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

For research use only

Growth Conditions

37 ℃, 5% CO2

Cell Type

Pericyte

Growth Mode

Adherent

Product Type

Ocular Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial

Frequently Asked Questions

  • What are Human Retinal Pericyte Cells?

    Human Retinal Pericyte Cells are specialized cells that wrap around the endothelial cells of retinal capillaries. They play a critical role in maintaining the structural integrity and function of the retinal blood-brain barrier and regulate blood flow in the retina.

  • What are the typical functions of Human Retinal Pericyte Cells?

    Human Retinal Pericyte Cells regulate capillary blood flow, support endothelial cell health, promote vessel stability, and maintain the structural integrity of retinal vasculature. They also play a role in angiogenesis and response to injury.

  • How are Human Retinal Pericyte Cells isolated?

    These cells are typically isolated from human retinal tissue by enzymatic digestion, followed by selective culture techniques that enrich for pericyte populations. This process yields cells that retain their functional characteristics for use in research.

  • How does the loss of Human Retinal Pericyte Cells contribute to diabetic retinopathy?

    Pericyte loss is a hallmark of diabetic retinopathy, a common complication of diabetes. Without pericytes, retinal capillaries become more permeable, leading to vascular leakage, retinal edema, and eventually vision loss. Studying these cells helps researchers understand the progression of this disease.

  • What are the potential applications of Human Retinal Pericyte Cells in research?

    These cells are used in research focused on retinal vascular health, neurovascular diseases, and vascular dysfunctions such as diabetic retinopathy. They are also utilized in tissue engineering and regenerative medicine studies aiming to repair or replace damaged retinal vasculature.

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