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Human Renal Proximal Tubule Cells | ||||
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| Product Name | Human Renal Proximal Tubule Cells | |||
| Price | Get Quote | |||
| Cat.No | ABC-TC4248 | Species | Human | |
| Size/Quantity | 1 vial | Biosafety Level | 1 | |
| Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
| Description | Renal proximal tubule cells (RPTCs) form single-layer epithelium that covers the basement membrane. They are responsible for the reabsorption of most solutes from the glomerular filtrate and the excretion of metabolic wastes and xenobiotics into the tubule lumen. RPTCs exhibit apicobasal polarity, which is essential for renal filtration. Renal proximal convoluted tubule epithelial cells express different enzymes in the urine and are involved in drug transportation and metabolism. RPTCs are sensitive to injury. When exposed to toxic or ischemic conditions, their death can lead to acute or chronic kidney disease. Why choose Human Renal Proximal Tubule Cells (HRPTCs) from AcceGen? HRPTCs are isolated from human kidneys using AcceGen’s advanced technology. Cells at passage one are cryopreserved to ensure the best viability. Each vial contains more than 5×10^5 cells in 1ml volume. HRPTCs are characterized by the expression of cytokeratin-18 and/or -19 using immunofluorescence. HRPTCs are guaranteed for further expansion of at least 15 doublings following protocols provided by AcceGen. | |||
| Disease | Normal | |||
| Source Organ | Kidney | |||
| Quality Control | All cell lots test negative for HIV-1, HBV, HCV, mycoplasma, yeast, fungi, and other pathogens. | |||
| Recommended Medium And Supplement | ABM-TM4248 Human Renal Proximal Tubule Cells Medium Kit | |||
| Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
| Application | For research use only Due to their significant role in renal homeostasis, human renal proximal tubule cells provide a useful tool for studying the biology and pathophysiology of renal tubular cells in vitro. They can be applied to research such as: – HRPTCs repair mechanism after injury and their role in the progression of renal fibrosis. – Intercellular talk between HRPTCs and other cells. – High-throughput screening of drugs and toxicities. – Role in renal diseases such as tubular necrosis, tubulointerstitial injury, nephrotoxicity, and renal cancer. | |||
| Key Features | – Backed by AcceGen advanced technology – Cryopreserved for highest viability and plating efficiency – Quality-guaranteed for accurate results – Timely technical support for best experimental outcomes | |||
| Growth Conditions | 37 ℃, 5% CO2 | |||
| Cell Type | Tubular Cell | |||
| Growth Mode | Adherent | |||
| Product Type | Renal Cells | |||
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