critical role in the kidney. In tissue morphogenesis, the formation of tubule is significantly affected by the polarization of renal epithelial cells. It is important to establish and maintain renal epithelial polarity for a normal excretion and resorption. In cases of acute kidney injury, it’s renal epithelial cells rather than human stem cells, that demonstrate a responsive capacity for rapid proliferation to facilitate the repair of injured proximal tubules. Human renal epithelial cells are a heterogeneous population of epithelial cells due to the diverse epithelia in kidney.
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