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Human Prostate Stromal Cells

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Product Name

Human Prostate Stromal Cells

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Cat.No

ABC-TC4042

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Human Prostate Stromal Cells are primary human cells characterized by their bipolar morphology, crucial for the glandular function of generating fluid with essential roles in reproduction. When stimulated by TGF-β, these cells express various growth factors and cytokines, such as IL-6 and BMP-6, which synergistically induce androgen receptor (AR) activation when co-cultured with prostate cancer cells. Additionally, these stromal cells express the progesterone receptor, enabling them to regulate cancer cell mobility. Moreover, estrogen plays a role in promoting the proliferation of human prostate stromal cells through the activation of the ERK pathway, further emphasizing their significance in prostate physiology and pathology.

 

Why choose Human Prostate Stromal Cells from AcceGen?

Choosing Human Prostate Stromal Cells from AcceGen ensures high quality and reliable performance. These cells are guaranteed through 15 population doublings and exhibit positive vimentin staining and negative pan cytokeratin staining. With cryopreservation at third or fourth passage, the cells arrive in optimal condition. Additionally, rigorous testing confirms the absence of mycoplasma, bacteria, yeast, and fungi, while HIV-1, hepatitis B, and hepatitis C are not detected in all donors and/or cell lots.

Disease

Normal

Source Organ

Prostate

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

Human Prostate Stromal Cells find diverse applications in various areas of research and medicine. In the context of benign prostatic hyperplasia (BPH), prostatitis, and prostate cancer, these cells serve as valuable tools for understanding disease mechanisms and potential therapeutic targets. Moreover, they play a crucial role in procreation research, offering insights into male reproductive physiology. Additionally, Human Prostate Stromal Cells are instrumental in drug discovery, aiding in the development and testing of novel therapies to combat prostate-related disorders and improve patient outcomes. Their versatility and relevance make them essential for advancing our understanding and treatment of prostate-related conditions.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Stromal Cell

Growth Mode

Adherent

Product Type

Male Reproductive Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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