Adipocytes play an important role in energy storage and metabolism. Adipocyte differentiation is a developmental process that is critical for metabolic homeostasis and nutrient signaling. It is controlled by complex actions involving gene expression and signal transduction. Preadipocytes are present throughout adult life in adipose tissue and can proliferate and differentiate into mature adipocytes according […]
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Human preadipocytes-visceral (HPA-v) refer to precursor cells that have the potential to differentiate into mature adipocytes (fat cells) specifically found in visceral adipose tissue. Visceral adipose tissue is the fat that surrounds internal organs, such as the liver, pancreas, and intestines, and is distinct from subcutaneous fat found beneath the skin.
Preadipocytes are undifferentiated cells that can undergo a process called adipogenesis, where they mature into adipocytes. The study of preadipocytes helps researchers understand the processes involved in fat tissue development, function, and regulation. In the context of “visceral,” it indicates a specific subset of preadipocytes derived from or with the potential to differentiate into fat cells found in visceral adipose tissue.
HPA-v from AcceGen Research Laboratories are isolated from human visceral fat tissue. HPA-v are cryopreserved at primary culture and delivered frozen. Each vial contains >1 x 10^6 cells in 1 ml volume. HPA-v are characterized by immunofluorescent method with antibodies to CD44, CD90 and lipid staining after differentiation. HPA-v are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HPA-v are guaranteed to further culture at the conditions provided by AcceGen Research Laboratories.
Why choose ABC-TC3759 Human Preadipocytes-Visceral from AcceGen?
Unlock the potential of groundbreaking research with AcceGen’s Human Preadipocytes-Visceral (HPA-v).
Rigorous Quality Assurance
All HPA-v cells undergo extensive testing, ensuring they are free from mycoplasma, bacteria, yeast, and fungi. Trust in the purity of your cell cultures.
Convenient Cryopreservation
HPA-v cells are cryopreserved at the primary culture stage and delivered frozen, ensuring viability and convenience for your experimental needs.
High Cell Density
Each vial contains over 1×10^6 cells in a 1mL volume, offering a plentiful supply for your experiments.
Immunofluorescent Characterization
Characterized by immunofluorescent methods using antibodies to CD44 and CD90, along with lipid staining after differentiation, ensuring the identity and functionality of the cells.
Stringent Safety Measures
HPA-v cells are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi, meeting the highest standards of safety in cell culture.
Product Code
HPA-v
Species
Human
Cat.No
ABC-TC3759
Quality Control
All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category
Primary Cells
Size/Quantity
1 vial
Cell Type
Preadipocyte
Shipping Info
Dry Ice
Growth Conditions
37 ℃, 5% CO2
Source Organ
Visceral
Disease
Normal
Biosafety Level
1
Storage
Liquid Nitrogen
Product Type
Adipose Cells/Preadipocytes
Citation
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
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Application
FOR RESEARCH USE ONLY
Human Preadipocytes-Visceral are valuable tools in biomedical research, particularly in studies related to obesity, metabolic disorders, and adipose tissue biology.
Here are the main fields that can be studied:
Adipogenesis Studies
Preadipocytes are precursor cells that can differentiate into mature adipocytes. Researchers use HPA-v cells to study the process of adipogenesis, which is the formation and development of fat cells.
Obesity and Metabolic Research
Understanding the molecular and cellular mechanisms involved in obesity and metabolic disorders is a critical area of research. HPA-v cells provide a human-relevant model to investigate how visceral adipose tissue contributes to these conditions.
Drug Development and Screening
HPA-v cells are used as a tool for drug development and screening in the context of obesity-related conditions. Researchers can test the effects of various compounds on adipocyte differentiation, lipid metabolism, and other relevant processes.
Disease Modeling
HPA-v cells can be employed to create in vitro models of diseases related to visceral adipose tissue, providing insights into the pathology of conditions such as metabolic syndrome, diabetes, and cardiovascular diseases.
Nutrition and Environmental Impact
Studying the effects of different nutritional components and environmental factors on adipocyte behavior is essential for understanding lifestyle-related impacts on health. HPA-v cells can be used to explore how diet and environmental exposures influence adipose tissue function.
Cellular and Molecular Biology Research
HPA-v cells serve as a valuable tool for broader studies in cellular and molecular biology. Researchers can explore signal transduction pathways, gene expression profiles, and other cellular processes related to adipose tissue biology.
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