Human Placental Vascular Endothelial Cells

Human Placental Vascular Endothelial Cells (HPVEC) are derived from the healthy human placenta, an intricately vascularized organ vital for fetal nourishment, hormone production, waste elimination, and fetal protection. This remarkable organ boasts an expansive vascular network covering a vast 15m² surface area when fully developed. Throughout pregnancy, the placental vasculature undergoes significant remodeling, driven in part by the proliferation and elongation of endothelial cells. Dysfunctions in these endothelial cells can lead to placental insufficiency, intrauterine growth restriction, and pre-eclampsia, highlighting the pivotal role of HPVECs in understanding and potentially addressing critical pregnancy-related complications.

Why choose Human Placental Vascular Endothelial Cells from AcceGen?

Human Placental Vascular Endothelial Cells from AcceGen are cryopreserved at passage one, with each vial containing more than 5×10⁵ cells in a 1mL volume. These cells are characterized through immunofluorescence using vWF/Factor VIII-specific antibodies, ensuring their authenticity. Moreover, they are guaranteed to expand for up to 10 population doublings under the specified conditions, offering a reliable and valuable resource for research and experimentation.