Mature red blood cells (RBCs, also called erythrocytes) are cells separated from blood and named for its red color. Human RBCs are developed in adult bone marrow through erythropoiesis. During erythroid maturation, RBCs lose nucleus and most organelles to accommodate maximum space for hemoglobin. Hemoglobin is an iron-rich protein which gives erythrocytes the red color. It also enables mature erythrocytes to transport oxygen to organs and carry carbon dioxide back to the lungs to accomplish gas exchanges. The loss of nuclei makes human RBC oval biconcave disks, appearing dumbbell-shaped in profile so that they can acquire an extraordinary degree of deformability and be flexible enough to pass through extremely small blood vessels.
AcceGen Human Red Blood Cells are isolated from peripheral blood through positive or negative selection.
Why Choose RBCs from AcceGen?
AcceGen provides cryopreserved Human PB red blood cells/mature erythrocytes for the best viability and plating efficiency. AcceGen Human RBCs are collected from healthy donor peripheral blood by density gradient. Donors are tested negative for HIV, HBV, and HCV. Peripheral blood are collected in acid-citrate-dextrose formula A (ACDA) by leukapheresis.
