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Primary Cells

Human PB Neutrophils

  • BSL
  • 171
Neutrophils compose between 40-75% of white blood cells in the body. They serve as first responders of the inflammatory response of the immune system.
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  • High Purity Levels
  • Precision and Reliability
  • Customization Options
Species

Human

Cat.No

ABC-TC4289

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

10M

Cell Type

Neutrophil

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Peripheral Blood

Disease

Normal

Storage

Liquid Nitrogen

Product Type

Immune Cells

Key Features

-Backed by AcceGen advanced technology
-Cryopreserved for highest viability and plating efficiency
-Quality-tested for accurate results
-Expert teams to provide timely support and assist best experimental outcomes

Description

Neutrophils, also known as polymorphonuclear (PMN) leukocytes, are the most abundant type in the whole blood. They are the first line of defense in the immune system against pathogens. There are three ways for neutrophils to perform antibacterial function: phagocytosis, degranulation, or the release of neutrophil extracellular traps (NETs). Increasing evidences suggest that neutrophils also involve in cytokine production, resolution of inflammation, cancer progression and adaptive immune responses. A high neutrophil-to-lymphocyte ratio (NLR) is often associated with poor prognostic in many malignancies. Recent coronavirus disease 2019 (COVID-19) outbreak has raised great attention on neutrophils where the NETs may contribute to organ damage and mortality.
Why choose Human PB Neutrophils from AcceGen?
AcceGen Human pb neutrophils are isolated from peripheral blood of fully consented IRB approved donors. Cells are cryopreserved immediately after isolation to ensure highest viability. Each vial contains more than 10 million cells. Human peripheral blood neutrophils are isolated by negative immunomagnetic selection and characterized with the cell surface marker CD16+CD45+CD66b+. All cell lots are tested negative for HIV-1, HBV, HCV and other pathogens. Cells should be preserved in Liquid Nitrogen vapor phase upon receipt.

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Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

  • For research use only

  • Human peripheral blood (PB) neutrophil provide an ideal cell culture model for studying its role in immune homeostasis, inflammation response and cancer biology. They have wide applications for studying:
  • – The protective role of neutrophils and the recruitment mechanisms that initated by various inflammatory mediators
  • – The formation of NETs and their potential role in immunity and disease, especially in cancer and COIVD-19 cases
  • – Validation on the existence of neutrophil subsets according to their phenotypic and functional heterogenecity
  • – Various neutrophil recruitment mechanisms in different tissues
  • – Neutrophils and tumour initiation, growth and metastasis

Inquiring Human PB Neutrophils

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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