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Human Parathyroid Cells

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Home | Primary Cells | Human Primary Cells | Endocrine System Primary Cells | Human Parathyroid Cells

Human parathyroid cells are derived from human parathyroid gland, an important endocrine organ located adjacent to the thyroid gland. The parathyroid consists of 4 small glands located behind the thyroid gland. Parathyroid cells are primarily responsible for the synthesis and secretion of parathyroid hormone (PTH), a polypeptide hormone, in response to decrease serum calcium levels. PTH acts on bones, kidneys and small intestine. The major controller of PTH synthesis and secretion is extracellular free (ionized) calcium. As serum calcium levels decrease, PTH secretion from the parathyroid glands increases. When serum calcium levels rise, this acts as a negative feedback loop, signaling the parathyroid glands to stop releasing PTH.

 

Why choose Human Parathyroid Cells from AcceGen?

AcceGen’s human parathyroid cells are derived from human parathyroid gland. They are maintained under standard culture conditions (37℃, 5% CO2) and cells are at least 5 x 105 cell/vial. Cells are high vitality, and are negative for mycoplasma, bacteria, yeast and fungi.

Species

Human
Cat.No

ABC-TC110L
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Primary Cells
Size/Quantity

1 vial
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Parathyroid
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Parathyroid Cells

Citation

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Application

  • FOR RESEARCH USE ONLY

  • Since the precise manipulation of PTH secretion in parathyroid tissue and its underlying molecular mechanisms still remain unclear, parathyroid cells can be used for PTH-related experimental studies. In addition, They can also be used for studies on parathyroid differentiation and development, which is of great significance for identifying potential methods and drugs for the treatment of parathyroid-related diseases.

Frequently Asked Questions

  • What are Human Parathyroid Cells?

    Human parathyroid cells are specialized cells located in the parathyroid glands, which are small endocrine glands situated behind the thyroid gland. These cells play a crucial role in regulating calcium levels in the blood by secreting parathyroid hormone (PTH).

  • What is the primary function of parathyroid hormone (PTH)?

    PTH regulates calcium and phosphate levels in the blood. It increases blood calcium levels by stimulating the release of calcium from bones, increasing calcium absorption in the intestines, and promoting calcium reabsorption in the kidneys.

  • What are the primary applications of human parathyroid cells in research?

    These cells are used in various research applications including studies on calcium homeostasis, bone metabolism, endocrine function, and the development of treatments for parathyroid-related disorders such as hyperparathyroidism and hypoparathyroidism.

  • What are the key markers used to identify human parathyroid cells?

    Key markers for human parathyroid cells include parathyroid hormone (PTH) and calcium-sensing receptors (CaSR). These markers are used to confirm the identity and purity of the cells in research studies.

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