Human Pancreatic Type 1 Diabetic Islets of Langerhans
1
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The Human Pancreatic Type 1 Langerhans Cells was derived from Human Pancreas. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.
Species | Human |
Cat.No | ABC-H0093X |
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Product Category | Primary Cells |
Size/Quantity | 1 vial |
Cell Type | Islets of Langerhan |
Shipping Info | Dry Ice |
Growth Conditions | 37 ℃, 5% CO2 |
Source Organ | Islet |
Disease | Type 1 Diabetic |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Pancreatic Cells |
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For research use only
These are clusters of pancreatic cells isolated from individuals with Type 1 Diabetes. They include beta cells, which are responsible for insulin production, and are typically obtained from donor pancreatic tissue through enzymatic digestion and density gradient centrifugation.
These islets are used in research focused on Type 1 Diabetes, including studies on insulin production, beta-cell function and regeneration, autoimmune mechanisms, and the development of new diabetes treatments.
In Type 1 Diabetes, the beta cells in the islets are damaged or destroyed by an autoimmune response, leading to reduced or absent insulin production. This is a key difference compared to non-diabetic islets, which have functioning beta cells.
No, Human Pancreatic Type 1 Diabetic Islets of Langerhans cannot be passaged in culture. These are primary cells with a limited lifespan, and they do not proliferate like cell lines. Once isolated, the islets can be maintained in culture for a limited period to study their function, but they will not divide or generate new islets. For ongoing studies, new islets must be isolated from donor tissue.