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Primary Cells

Human Pancreatic Type 1 Diabetic Islets of Langerhans

  • BSL

    1

  • 133
The Human Pancreatic Type 1 Langerhans Cells was derived from Human Pancreas. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.
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The Human Pancreatic Type 1 Langerhans Cells was derived from Human Pancreas. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.

Species

Human

Cat.No

ABC-H0093X

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial

Cell Type

Islets of Langerhan

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Islet

Disease

Type 1 Diabetic

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Pancreatic Cells

Citation

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Application

  • For research use only

Frequently Asked Questions

  • What are Human Pancreatic Type 1 Diabetic Islets of Langerhans, and how are they obtained?

    These are clusters of pancreatic cells isolated from individuals with Type 1 Diabetes. They include beta cells, which are responsible for insulin production, and are typically obtained from donor pancreatic tissue through enzymatic digestion and density gradient centrifugation.

  • What are primary research applications for Human Pancreatic Type 1 Diabetic Islets of Langerhans?

    These islets are used in research focused on Type 1 Diabetes, including studies on insulin production, beta-cell function and regeneration, autoimmune mechanisms, and the development of new diabetes treatments.

  • How do Human Pancreatic Type 1 Diabetic Islets of Langerhans differ from non-diabetic islets?

    In Type 1 Diabetes, the beta cells in the islets are damaged or destroyed by an autoimmune response, leading to reduced or absent insulin production. This is a key difference compared to non-diabetic islets, which have functioning beta cells.

  • Can Human Pancreatic Type 1 Diabetic Islets of Langerhans be passaged in culture?

    No, Human Pancreatic Type 1 Diabetic Islets of Langerhans cannot be passaged in culture. These are primary cells with a limited lifespan, and they do not proliferate like cell lines. Once isolated, the islets can be maintained in culture for a limited period to study their function, but they will not divide or generate new islets. For ongoing studies, new islets must be isolated from donor tissue.

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Tags

  • Human (1729)
  • Pancreatic (9)
  • Type I Diabete (13)
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