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Human Pancreatic Type 1 Diabetic Islets of Langerhans | ||||
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| Product Name | Human Pancreatic Type 1 Diabetic Islets of Langerhans | |||
| Price | Get Quote | |||
| Cat.No | ABC-H0093X | Species | Human | |
| Size/Quantity | 1 vial | Biosafety Level | 1 | |
| Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
| Description | The Human Pancreatic Type 1 Langerhans Cells was derived from Human Pancreas. Each vial contains at least 1×10^6 cells per ml and is delivered frozen. | |||
| Disease | Type 1 Diabetic | |||
| Source Organ | Islet | |||
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. | |||
| Recommended Medium And Supplement | ABM-H0093X Human Pancreatic Type 1 Diabetic Islets of Langerhans Medium Kit | |||
| Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
| Application | For research use only | |||
| Growth Conditions | 37 ℃, 5% CO2 | |||
| Cell Type | Islets of Langerhan | |||
| Growth Mode | Adherent | |||
| Product Type | Pancreatic Cells | |||
| Product Image |  | |||
Frequently Asked Questions
What are Human Pancreatic Type 1 Diabetic Islets of Langerhans, and how are they obtained?
These are clusters of pancreatic cells isolated from individuals with Type 1 Diabetes. They include beta cells, which are responsible for insulin production, and are typically obtained from donor pancreatic tissue through enzymatic digestion and density gradient centrifugation.
What are primary research applications for Human Pancreatic Type 1 Diabetic Islets of Langerhans?
These islets are used in research focused on Type 1 Diabetes, including studies on insulin production, beta-cell function and regeneration, autoimmune mechanisms, and the development of new diabetes treatments.
How do Human Pancreatic Type 1 Diabetic Islets of Langerhans differ from non-diabetic islets?
In Type 1 Diabetes, the beta cells in the islets are damaged or destroyed by an autoimmune response, leading to reduced or absent insulin production. This is a key difference compared to non-diabetic islets, which have functioning beta cells.
Can Human Pancreatic Type 1 Diabetic Islets of Langerhans be passaged in culture?
No, Human Pancreatic Type 1 Diabetic Islets of Langerhans cannot be passaged in culture. These are primary cells with a limited lifespan, and they do not proliferate like cell lines. Once isolated, the islets can be maintained in culture for a limited period to study their function, but they will not divide or generate new islets. For ongoing studies, new islets must be isolated from donor tissue.
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