Human OX40 (Luc) HEK293 Reporter Cell

The Human OX40 (Luc) HEK293 Reporter Cell was engineered to not only express NF-κB signaling response element, but also express the receptor full length human OX40 (Gene ID: 7293), which can drive luciferase expressing systems by OX40 ligand/agonist antibody stimulation. When stimulated with human OX40 ligand protein, the OX40 ligand/OX40 interaction drives NF-κB-mediated luminescence. Inhibition of OX40 ligand binding to OX40 by either anti-OX40 ligand or anti-OX40 antibodies results in a decrease in luminescence.