Human Ovarian Surface Epithelial Cells are primary cells derived from the outer layer of the human ovary. In vivo, they display a diverse morphology ranging from squamous to cuboidal to low columnar. These cells play an active role in cyclical ovulatory follicular rupture and subsequent repair. They express various peptide hormones, sex steroids, growth factors, and receptors. Notably, when co-cultured with endometrial stromal cells in an estrogen-rich environment, these cells exhibit gland formation. Moreover, when cultured on two layers of extracellular matrix and collagen gel, they demonstrate a mesenchymal property, reflecting their phenotypic plasticity.
Inquiring Human Ovarian Surface Epithelial Cells
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